$$ \begin{aligned} 1-(2+3)\cdot4-5\cdot6 &= 0&& \text{simplify left side} \\[1 em]1-5\cdot4-30 &= 0&& \\[1 em]1-20-30 &= 0&& \\[1 em]-49 &= 0&& \\[1 em] \end{aligned} $$
Since the statement $ \color{red}{ -49 = 0 } $ is FALSE, we conclude that the equation has no solution.
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