$$ \begin{aligned} (16-4)\cdot5-\frac{80}{5} &= 0&& \text{multiply ALL terms by } \color{blue}{ 5 }. \\[1 em]5(16-4)\cdot5-5\cdot\frac{80}{5} &= 5\cdot0&& \text{cancel out the denominators} \\[1 em]300-80 &= 0&& \text{simplify left side} \\[1 em]220 &= 0&& \\[1 em] \end{aligned} $$
Since the statement $ \color{red}{ 220 = 0 } $ is FALSE, we conclude that the equation has no solution.
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