Step 1: First we have to write polynomials in descending order.
$$ \begin{aligned} P(x) &= -5x^3+6 \\ Q(x) &= 4x^3+2x \\ \end{aligned} $$Step 2: Write second polynomial below the first one. Making sure like terms are lined up.
$$ \begin{array}{lrrr} & -5x^3 & & 6 \\ \color{red}{ - } & 4x^3 & 2x & \\ \hline \end{array} $$Step 3: Change ALL the signs in the second row.
$$ \begin{array}{lrrr} & -5x^3 & & 6 \\ \color{red}{ - } & -4x^3 & -2x & \\ \hline \end{array} $$Step 4: Combine like terms (add each column):
$$ \begin{array}{lrrr} & -5x^3 & & 6 \\ \color{red}{ - } & -4x^3 & -2x & \\ \hline & -x^3 & 2x & 6 \end{array} $$