Step 1: Write second polynomial below the first one. Making sure like terms are lined up.
$$ \begin{array}{lrrrr} & -4s^4 & 3s^3 & & \\ \color{red}{ - } & & & 2s & -3 \\ \hline \end{array} $$Step 2: Change ALL the signs in the second row.
$$ \begin{array}{lrrrr} & -4s^4 & 3s^3 & & \\ \color{red}{ - } & & & -2s & 3 \\ \hline \end{array} $$Step 3: Combine like terms (add each column):
$$ \begin{array}{lrrrr} & -4s^4 & 3s^3 & & \\ \color{red}{ - } & & & -2s & 3 \\ \hline & -4s^4 & 3s^3 & 2s & -3 \end{array} $$