The roots of polynomial $ p(x) $ are:
$$ \begin{aligned}x_1 &= 5\\[1 em]x_2 &= -5\\[1 em]x_3 &= 3i\\[1 em]x_4 &= -3i \end{aligned} $$Step 1:
Use rational root test to find out that the $ \color{blue}{ x = 5 } $ is a root of polynomial $ x^4-16x^2-225 $.
The Rational Root Theorem tells us that if the polynomial has a rational zero then it must be a fraction $ \dfrac{ \color{blue}{p}}{ \color{red}{q} } $, where $ p $ is a factor of the constant term and $ q $ is a factor of the leading coefficient.
The constant term is $ \color{blue}{ 225 } $, with a single factor of 1, 3, 5, 9, 15, 25, 45, 75 and 225.
The leading coefficient is $ \color{red}{ 1 }$, with a single factor of 1.
The POSSIBLE zeroes are:
$$ \begin{aligned} \dfrac{\color{blue}{p}}{\color{red}{q}} = & \dfrac{ \text{ factors of 225 }}{\text{ factors of 1 }} = \pm \dfrac{\text{ ( 1, 3, 5, 9, 15, 25, 45, 75, 225 ) }}{\text{ ( 1 ) }} = \\[1 em] = & \pm \frac{ 1}{ 1} \pm \frac{ 3}{ 1} \pm \frac{ 5}{ 1} \pm \frac{ 9}{ 1} \pm \frac{ 15}{ 1} \pm \frac{ 25}{ 1} \pm \frac{ 45}{ 1} \pm \frac{ 75}{ 1} \pm \frac{ 225}{ 1} ~~ \end{aligned} $$Substitute the possible roots one by one into the polynomial to find the actual roots. Start first with the whole numbers.
We can see that $ p\left( 5 \right) = 0 $ so $ x = 5 $ is a root of a polynomial $ p(x) $.
To find remaining zeros we use Factor Theorem. This theorem states that if $ \dfrac{p}{q} $ is root of the polynomial then the polynomial can be divided by $ \color{blue}{qx − p} $. In this example we divide polynomial $ p $ by $ \color{blue}{ x-5 }$
$$ \frac{ x^4-16x^2-225}{ x-5} = x^3+5x^2+9x+45 $$Step 2:
The next rational root is $ x = 5 $
$$ \frac{ x^4-16x^2-225}{ x-5} = x^3+5x^2+9x+45 $$Step 3:
The next rational root is $ x = -5 $
$$ \frac{ x^3+5x^2+9x+45}{ x+5} = x^2+9 $$Step 4:
The solutions of $ x^2+9 = 0 $ are: $ x = 3 i ~ \text{and} ~ x = -3 i $.
You can use step-by-step quadratic equation solver to see a detailed explanation on how to solve this quadratic equation.