The GCD of given numbers is 1.
Step 1 : Find prime factorization of each number.
$$\begin{aligned}301 =& 7\cdot43\\[8pt]981 =& 3\cdot3\cdot109\\[8pt]449 =& 449\\[8pt]573 =& 3\cdot191\\[8pt]\end{aligned}$$(view steps on how to factor 301, 981, 449 and 573. )
Step 2 : Put a box around factors that are common for all numbers:
$$\begin{aligned}301 =& 7\cdot43\\[8pt]981 =& 3\cdot3\cdot109\\[8pt]449 =& 449\\[8pt]573 =& 3\cdot191\\[8pt]\end{aligned}$$Note that in this example numbers do not have any common factors.
Step 3 : Multiply the boxed numbers together:
Since there is no boxed numbers we conclude that $~\color{blue}{ \text{GCD = 1} } $.